New Breakthrough! Nano-scale "surgery" - no incision, only a 1mm puncture, precisely "destroying" tumor cells!NanoKnife, also known as irreversible electroporation, is a new tumor ablation technology. It uses high-voltage pulses to create nano-scale perforations in tumor cells, rapidly disrupting intracellular homeostasis and inducing apoptosis while protecting normal tissue.It is suitable for treating solid tumors including pancreatic, liver, and renal cancer, benefiting many mid-to-late stage tumor patients.
NanoKnife (Nanoknife) is a groundbreaking minimally invasive treatment technology, now applied for the first time in surgical ablation. Its unique principles and techniques bring more possibilities to tumor treatment.
How It Works
The core technology uses probes to generate micro-scale high-voltage pulses within or around the ablation zone. These pulses disrupt cell membranes, inducing apoptosis without heating or cooling tissue. This distinguishes NanoKnife from traditional cryoablation and microwave ablation, enabling precise ablation while maximally protecting surrounding normal tissue.
Technical Advantages
1、No thermal effect, reduced damage：NanoKnife generates no heat during treatment, causing no thermal damage. Important structures such as blood vessels, bile ducts, and nerves lack lipid bilayer structures and are not damaged by high-voltage pulses, maintaining their function.
2、Precise and controllable：Under ultrasound or CT guidance, the system accurately calculates the shape and volume of the ablation zone and determines the probe's effective range. Treatment plans are precise to the millimeter level, providing individualized treatment.
3、Fast and efficient：Treating a lesion under 2cm typically takes no more than 5 minutes. NanoKnife induces apoptosis within minutes, and patients can be discharged the same day, greatly reducing recovery time.
4、Natural apoptosis, no fibrotic residue：NanoKnife simulates normal cell death through irreversible electroporation. The treated area is cleared by phagocytes and gradually replaced by normal tissue, leaving no fibrotic traces.
Treatment Outcomes：After NanoKnife treatment, microscopy shows clear boundaries between treated and untreated areas. Blood vessels larger than 1mm, major vessels, and ducts are unaffected and maintain normal function. After 1-3 months, CT scans show virtually no treatment traces.
Application Prospects
The no-thermal-effect and precision features make it especially suitable for tumors near important blood vessels and nerves. This technology is becoming a "superhero" in minimally invasive tumor treatment, providing safer and more efficient options.
NanoKnife provides entirely new solutions for treating many complex lesions. along withtechnology的continuouslydevelopment, itaftertumortreatment field'sApplication Prospectswill be even broader.