In an era of rapidly advancing medical technology, Shenzhen Huaqiao Hospital once again stands at the forefront, having successfully introduced the internationally leading third-generation CombiKnife (composite cold-hot ablation system), bringing new treatment options and hope to tumor patients.
So what exactly is CombiKnife? How does it achieve precision, painlessness, and the integration of cold and heat? Today, let us unveil the mystery of CombiKnife.
What is CombiKnife
CombiKnife, fully named the multimodal cryo-thermal ablation treatment system, is an innovative medical device integrating cryotherapy, thermotherapy, and ablation. Compared with traditional surgery, CombiKnife's greatest advantage is its minimally invasive nature. It uses a needle only1.7millimeter ultra-fineablation needle, throughprecisionpuncturedirectly reachestumor lesions, achieving the concept of using a needle instead of a scalpelTreatment Outcomes。This design greatly reduces patient trauma and pain, accelerates post-operative recovery, and improves quality of life.
Core Technology - Dual Cold-Hot Ablation
The core of CombiKnife technology lies in its ability to rapidly switch between deep cold at -196°C and high heat above 80°C. This extreme temperature difference causes tumor cells to undergo dramatic physical changes during cold-hot alternation, triggering cell swelling and rupture, ultimately leading to coagulative necrosis of tumor tissue.
01Deep Cold Treatment
At -196°C, ice crystals rapidly form inside and outside tumor cells, causing cell membrane rupture and cell structure destruction. Meanwhile, low temperature forms ice crystals in micro-veins and micro-arteries, destroying small vessels, causing local hypoxia,furtherintensifyingtumor cells的dead。
02 High Temperature Treatment
Subsequently,ablationprobe将temperaturerapidly raised to80℃or more, fortumor tissueheating. High temperature causescancausingtumor cellsprotein denaturation,cell membranerupture,fromthereby completely killingtumor cells。In addition，High temperature can alsoablationpuncture needletract, preventingbleedingand preventingtumorneedle tract seedingand metastasis。
Technical Advantages·precisionsafe
CombiKnifetechnologyanother majoradvantagesafterlies in its high-precision treatment range.afterCT、ultrasound, etc.imaging equipment的guidance,doctorcan clearly seetumorposition and size,from而precisionpreciselyablationprobeinsertingtumortargeted site.Thisimaging-guidedprecision treatment，not onlyimprovedtreatment accuracy, while greatly reducing damage to surrounding normal tissues.
01real-time monitoring
afterDuring the treatment process,doctorcan useimaging equipmentreal-time monitoringablationboundaries, ensuring the treatment range is precisely accurate.Thisreal-time monitoringtechnology，makes得doctorcan and adjust treatment parameters in real time to achieve optimalTreatment Outcomes。
02超minimally invasive treatment
CombiKnifetechnologytreatment method is percutaneouspuncture, targetedablation. Becauseablationprobe的diameteris only2millimetersapproximately，Thereforetreatment incision is extremely small,patientspost-operativerecoveryrapid.This超minimally invasivetreatment method,not onlyto reduce了patientssuffering, while also shortening hospital stays,reducetreatment costs.
China Anti-Cancer Associationtumor hyperthermiaCommittee Standing Member, Shenzhen Huaqiao Hospital副President兼tumorDepartment DirectorProfessor Dong Wenguangintroduced,compared withradiofrequency ablation和microwave ablation，CombiKnifecryoablationnot onlyhas the advantages of minimal trauma,side effectslow,recovery快, etc.advantages, and also less frequently causes localpain。patients are suitable于tumor"adjacent to"painsensitive areas, such as: pleura≤1 cmor bones withand metastasiscausing bone destructiontumor patients, during the treatment processpatientspainlesssensation.
CombiKnifetechnologywith its uniquetemperaturecontrol and high-precision treatment range,significantlyenhancingtumor patients的survival rate和quality of life。Multipleclinical researchstudies show，CombiKnifetechnologyaftertreatmentliver cancer、lung cancer、pancreatic cancer, etc.varioussolidtumoraspectsachievedsignificantlyefficacy。
01widelysuitable性
CombiKnifetechnologysuitable于80%or more的tumortumor types，includingliver cancer、lung cancer、pancreatic cancer、thyroid cancer、prostate cancer, etc.varioussolidtumor。Thiswidely的suitablenature,makes得Morepatientscanto benefit fromthis创new technology。
02combined treatmentplan
CombiKnifetechnologynot onlycan be performed alone, or also and surgicalsurgery、radiationchemotherapy, etc.combinedmakestogether.Thiscombined treatmentplan，canfurtherimproveTreatment Outcomes，reducerecurrence rate和metastasis rate。
03enhancingimmune function
researchstudies show，CombiKnifetreatmenttechnologywithoutradiation和or chemical damage,not onlycan be repeated, and alsocanstimulating the body's ownimmune response，enhancingimmune cells的activity，from而furtherinhibitingtumor的growth和and spread。Thisimmuneenhancingeffect，makes得patientsafter treatmentcanbetterresisttumor recurrence和and metastasis。Therefore，CombiKnifetreatmenttechnologyis also called“green treatmenttechnology"。
third-generationCombiKnifetechnologyintroduction,not onlyis not onlyShenzhen Huaqiao Hospitalexisting treatmentapproachsupplement and upgrade, but also atumortreatment field'sprofound transformation.thistechnologybehind itinnovationconceptand advancedtechnology, heraldingIn the futuretumortreatment will become morepersonalized、precisionspecialized andefficientoriented. Looking ahead,In the future, along with medicaltechnology的continuouslyprogress andinnovation，Shenzhen Huaqiao Hospitalwill continue to uphold "patientpatients-centered""serviceconcept, committed to providingpatientshigher quality,efficient、personalizedmedical services, and promoting China'stumortreatment field'sdevelopmentcontributing its own strength.
About Us
As a comprehensive hospital integrating medical care, teaching, and research,hospital，Shenzhen Huaqiao Hospitalalways committed to introducing and promoting advanced medicaltechnology，Meanwhilebuilding a nationaltumor hyperthermiademonstration base, equipped withMRI、CT、DR、tumorwhole-bodyhyperthermia, deephyperthermia, superficialhyperthermiaand hyperthermic perfusion treatmentandcomposite cold-hotablation(CombiKnife)、 DSA interventional、 3Dtemplate printing, etc.a series of advancedtumorspecialtyequipment. For mid-to-advanced stagesolidtumorimplementing whole-bodyhyperthermiacombinedtumorarteryminimally invasive intervention, composite cold-hotablation treatment、tumortargetedimmunotherapy, gene therapy,traditional Chinese medicinefeaturestreatment, establishing afeatures、minimally invasive、greentreatmentplatform。